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| Definition: |
A test to detect the presence of strains of Clostridium difficile (C. difficile) toxin in the stool.
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| How the test is performed: |
A sample of a stool specimen is incubated in the laboratory with tissue culture cells and monitored for a specific reaction.
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| How to prepare for the test: |
Adults and children:
There are many ways to collect the samples. You can catch the stool on plastic wrap that is loosely placed over the toilet bowl and held in place by the toilet seat. Then put the sample in a clean container. One test kit supplies a special toilet tissue that you use to collect the sample, then put the sample in a clean container.
Infants and young children:
For children wearing diapers, you can line the diaper with plastic wrap. If the plastic wrap is positioned properly, isolating the stool from any urine output, mixing of urine and stool can be prevented for a better sample.
Do not mix urine, water, or toilet tissue in with the sample.
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| How the test will feel: |
There is no discomfort.
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| Why the test is performed: |
The test may be done when there is no identifiable cause of diarrhea or when antibiotic usage is associated with the diarrhea.
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| Normal Values: |
Normal stool organisms are present.
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| What abnormal results mean: |
Abnormal results may show C. difficile toxin in the stool.
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| What the risks are: |
There are no risks.
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| Special considerations: |
This test is usually reserved for when other causes of diarrhea have been ruled out.
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Review Date: 12/3/2001
Reviewed By: Andrew J. Muir, M.D. M.H.S., Division of Gastroenterology, Duke University Medical Center, Durham, NC. Review provided by VeriMed Healthcare Network.
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The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed physician should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. Copyright 2002 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.
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